The Organic Chemical Metrology Group (OCMG) in the Chemical Sciences Division at NIST develops, critically evaluates, and applies analytical methods based on liquid chromatography, gas chromatography, high-resolution mass spectrometry, vibrational and nuclear magnetic resonance spectroscopy, as related to analyses at trace and ultratrace concentration levels. OCMG is also responsible for the development and characterization of Standard Reference Materials (SRMs) to enhance chemical measurement comparability within the U.S. and to provide a basis for measurement comparability with other nations. SRMs developed and supported by OCMG are used to support clinical, food, environmental, and forensics analyses.

The OCMG will apply its knowledge and experience to study and identify trace organic impurities in solvents, such as ultra-pure water, used by the semiconductor industry. Knowledge and the levels of organic impurities can increase yields in semiconductor manufacturing. For the successful compound discovery of contaminants at ultratrace levels in the solvents, a sensitive gas chromatograph high-resolution mass spectrometer (GC-HRMS) is needed. Furthermore, the sample introduction system must be flexible to accommodate several types of injections, including liquid injection, solid-phase microextraction, headspace, dynamic headspace, and purge-and-trap. The procurement of a GC-HRMS will help meet research goals in the CHIPs program and increase the capability of the Chemical Sciences Division.

NIST is seeking information from sources that may be capable of providing a commercial solution that will achieve the objectives described above, in addition to the following essential requirements: 

NIST intends to acquire a GC-HRMS system that will be used for non-targeted analysis for compound discovery of contaminants at ultratrace levels in ultra-pure water and other solvents. The instrument must be able to reproducibly generate high-resolution and high-quality MS and MS/MS spectra that is capable of both electron ionization (EI) and chemical ionization (CI) to accurately identify unknown analytes. Extraction and concentration of organic analytes are anticipated, and hence, the instrument will need to have the capability of liquid injections, headspace (static and dynamic) injections, solid-microextraction (SPME), including Arrow SPME, and purge-and-trap. To protect hardware from momentary power interruptions, the instrument should also be procured with an uninterruptible power supply (UPS). The required equipment will need to consist of integrated instrument control and data analysis software.

No laboratory bench currently exists in the space and must also be included in the procurement package if the system is a benchtop instrument. The bench will need to be large enough for the proposed instrument and autosamplers (including purge and trap), support the weight of the equipment, and fit in the designated footprint. The data system (computer) can be placed on an existing lab bench adjacent to the space where the instrument will be placed. The footprint of the instrument, including the portable lab bench shall be no larger than 230 cm x 121 cm x 250 cm (width x depth x height). In addition, all uninstalled components must be able to fit within the door with dimensions of 109 cm x 236 cm. 

Line Item 0001:

Description:  Gas Chromatograph high-resolution mass spectrometer

Comment: System to include autosampler, GC, HRMS, computer system and software, and equipment needed for installation

Quantity:  1

1. Technical Specifications
   1. Resolution: >100,000 at m/z 200
   2. Mass accuracy: <5 ppm (external calibration), <2 ppm (internal lock mass calibration)
   3. Mass range: 30-1,500 m/z
   4. Analytical dynamic range: > 5 orders
   5. Sensitivity: instrument detection limit of <10 fg octafluoronaphthalene on column
   6. Ionization: Electron ionization (EI), positive ion chemical ionization (PCI), and negative ion chemical ionization
   7. Shall have MS/MS capability
   8. Acquisition types: full scan, select ion monitoring (SIM), selected reaction monitoring/multiple reaction monitoring, data-dependent acquisition
   9. Split/splitless injection with He Saver mode
   10. PTV injector with back flush capability
   11. Uninterruptible power supply (UPS) and supporting equipment to protect equipment against momentary power interruptions. The UPS shall be able to run off 208 V connected to a 45 A breaker. The UPS shall have a cord ending in a 6-50P.
   12. Oilless roughing pump.
   13. Autosampler with the capability of the following sampling techniques:
       1. Liquid injections
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